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Customer Hotline：+1 6193853151
Product Model：CytoLinx® GB Manufacturer nature：Manufacturer Update time：2025-07-21 Visits：134 Product catalog
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Detailed Introduction
Please be advised that this product is only available for sale and after-sales support in certain regions. For further details, kindly consult with your local sales representative. Thank you for your understanding.
Features of CytoLinX® GB 1-20 L Benchtop Glass Bioreactor
CytoLinX® GB Control Cabinet
The CLX-GB control cabinet includes control hardware and underlying hardware modules. The control hardware is built with Siemens win CC framework, which meets requirements from development to manufacturing and complies with 21 CFR Part 1.
The underlying hardware modules are all built with imported brands, featuring high stability. In addition, a variety of PAT tools can be flexibly configured to meet different customer needs and application scenarios.
ACLX-GB control cabinet can be interfacing with different models of glass vessels, achieving versatile use with a single unit.
The CLX-GB vessel adopts a top stirring mode and allows a flexible combination of microbubble and large bubble, promoting the optimization of the culture process, further improving cell density as well as maintaining cell viability.
Figure 2. CytoLinX® GB main control interface
Applications of CytoLinX® GB 1-20 L Benchtop Glass Bioreactor
CytoLinX® GB for ADC Conjugation Process Optimization
BioLink provides an automated platform for the optimization of the ADC conjugation process. Features such as precise temperature control and programmable automatic dosing ensure high repeatability and stability of the reaction system, and the kettle design is more feasible for manufacturing and linear scale-up. The synthesis platform has excellent scalability and can be equipped with online pH sensors to enhance process development monitoring and control. In addition, the automatic program is designed to significantly avoid errors caused by manual operations, thereby ensuring consistency between synthesis batches.
CytoLinX® GB for mRNA Production
The development difficulty and the key technical points of mRNA technology lie in the synthetic modification and delivery systems. In Vitro Transcription (IVT) is the most efficient method for batch synthesis of mRNA. It is a relatively complex enzymatic process that requires the addition of enzymes, nucleotides, and other related reagents, in addition to the DNA template. BioLink provides a fully automated IVT synthesis platform that enables efficient linear scale-up from lab-scale development to scale up production. With features such as precise temperature control and programmable automatic dosing, the CytoLinX® GB benchtop glass bioreactors ensure the high repeatability and stability of the synthesis system, and the automatic program design significantly avoids the errors caused by manual operations to ensure the consistency between synthesis batches.
Configuration of CytoLinX® GB 1-20 L Benchtop Glass Bioreactor
|
Vessel (single-wall) |
Total volume |
1 L |
3 L |
7 L |
15 L |
20 L |
|
Max. working volume |
0.8 L |
2.4 L |
5.6 L |
12 L |
16 L |
|
|
Min. working volume |
0.2 L |
0.6 L |
1.4 L |
3 L |
8 L |
|
|
Working height to diameter ratio (H/D) |
1.5/1 |
1.5/1 |
1.8/1 |
1.45/1 |
1.5/1 |
|
|
Material |
High silicon borate |
|||||
|
Vessel (jacket) |
Max. working volume |
NA |
2.4 L |
5.6 L |
12 L |
NA |
|
Min. working volume |
NA |
0.6 L |
1.4 L |
3 L |
NA |
|
|
Working diameter to height ratio (H/D) |
NA |
1.5/1 |
1.8/1 |
1.4/1 |
NA |
|
|
Jacket volume |
NA |
1.2 L |
2.4 L |
7.4 L |
NA |
|
|
Material |
High silicon borate |
|||||
|
Vessel cover |
Port |
M30*1 M18*1.5*3 10 mm*6 6 mm*3 |
M30*1 M18*1.5*6 12 mm*2 10 mm*9 |
M30*1 M18*1.5*6 12 mm*2 10 mm*10 |
69 mm*1 27 mm*6 12 mm*2 10 mm*10 |
69 mm*1 27 mm*6 12 mm*2 10 mm*10 |
|
Material |
SS316L |
|||||
|
Stirring system |
Mode |
Top servo brushless motor |
||||
|
Stirring speed |
0-1500 rpm |
|||||
|
Sensor |
pH |
Hamilton smart pH electrode, VP8 joint |
||||
|
DO |
Hamilton smart optical dissolved oxygen electrode, VP8 joint |
|||||
|
Temperature |
Pt 100, Grade A, 0-150°C |
|||||
|
Level/antifoam |
Resistance type, automatic level control for adding antifoam (optional) |
|||||
|
Others |
pCO2 electrode (optional), cell density electrode (optional), conductance (optional), Raman electrode (optional), etc. |
|||||
|
Gas control |
Ventilation mode |
Surface ventilation/deep ventilation |
||||
|
Gas type |
Air, O2, CO2, N2 |
|||||
|
Control method |
0-6 channel mass flow meter (MFC) /0-4 channel rotameter |
|||||
|
Gas distributor |
L-shaped bubble/annular bubble/microbubble (5-200 um) |
|||||
|
Tail gas |
Stainless steel condensing reflow (optional) |
|||||
|
Peristaltic pump |
Peristaltic pump |
2-4 variable speed pumps |
||||
|
Speed |
0.1-300 rpm |
|||||
|
Reserve external pump port |
0-2 variable speed pumps (optional) |
|||||
|
Temperature |
Control method |
Electric heating blanket (Single-wall vessel)/TCU heating (jacketed vessel) |
||||
|
Weighing |
Reserve external weight port |
0-4 variable speed weights (optional) |
||||
|
Control system |
Controller |
Industrial PLC |
||||
|
Interface |
23" PC |
|||||
|
Compliance |
Conforming to 21 CFR PART 11 |
|||||
|
Integrity test |
Integrity tester |
Detection range: 0-350 mbar (optional) |
||||
Ordering Information
1 L benchtop glass bioreactor
|
1 L benchtop glass bioreactor |
Cat No. |
Specification |
|
Glass reactor |
||
|
1 L glass reactor, single-wall (bracket, glass reaction vessel, stainless steel roof and bracket) |
CGB01LGS-001 |
1 L |
|
1 L glass reactor, jacket (bracket, glass reaction vessel, stainless steel roof and bracket) |
CGB01LGJ-001 |
1 L |
|
1 L single-wall glass reactor |
CGB01LVS-001 |
1 L |
|
1 L jacketed glass reactor |
CGB01LVJ-001 |
1 L |
|
1 L single-wall, jacketed universal stainless steel roof |
CGB01LSR-001 |
1 L |
|
1 L single-wall stainless steel bracket |
CGB01LSR-002 |
1 L |
|
1 L jacketed stainless steel bracket |
CGB01LSR-015 |
1 L |
|
Stir |
||
|
1 L mixing assembly |
CGB01LSR-003 |
OD: M30 |
|
1 L marine mixing paddle |
CGB01LSR-004 |
OD: 38 mm |
|
1 L flat blade turbine mixing paddle |
CGB01LSR-005 |
