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Chrom-Linx® Lab-scale Empty Chromatography Column
Brief description

High-Performance Empty Chromatography Columns


Chrom-LinX® Lab-scale Empty Chromatography Column is a family of chromatography column designed for simple operation, high pressure resistance and flexible adjustment, which are suitable for process development, process verification, quality testing and preparative small-scale sample purification.

Product Model: Glass tubes with inner diameter (i.d.) of 10 mm, 16 mm, 26 mm or 50 mm, and bed height of 200 mm, 4
Manufacturer nature:Manufacturer
Update time:2025-06-16
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Detailed Introduction

Features and Benefits of Chrom-LinX® Lab-scale Empty Chromatography Column

  • User-friendly design: Ergonomically design the components for easy grasping and handling

  • Clear view: Equipped with a measurement scale of glass tube for easy to predict and reach a predefined bed height and improving process reproducibility

  • High pressure resistance: compatible with common resins of different particle sizes allowing operation up to 20 bar* (2 MPa, 290 psi) pressure

  • Various sizes: Glass tubes with inner diameter (i.d.) of 10 mm, 16 mm, 26 mm or 50 mm, and bed height of 200 mm, 400 mm, 700 mm or 1000 mm provide a wide range of column volumes

  • High flexibility: Equipped with single/double adjustable capital for flexible expansion of column volumes

  • Easy to clean: Each component for easy assembling removing and cleaning

  • Compatibility: Supplied with tubing and connectors suitabling for a variety of common laboratory tomographic systems



Empty Chromatography Column

Fig 1. Chrom-LinX® Lab-scale Empty Chromatography Column


*The columns withstands pressures up to 7 bar (0.7 MPa, 101.5 psi) with 50 mm inner diameter.


Product Characteristics of Chrom-LinX® Lab-scale Empty Chromatography Column

Chrom-LinX® Lab-scale Empty Chromatography Column are available in two designs: single adjustable capital and double adjustable capital. The design of single adjustable capital mainly consists of a adjustable capital, a chromatography column tube and a fixed capital. The design of double adjustable capital replaces the fixed capital with an adjustable capital to extend the column volume (Fig 2).


Chrom-LinX® Lab-scale Empty Chromatography Column are equipped with 10 μm net ring (5 μm net ring being also optional), which are compatible with common resins of different particle sizes.


Glass Chromatography Column

Fig 2. Components of the Chrom-LinX® Lab-scale Empty Chromatography Column


Chemical Resistance of Chrom-LinX® Lab-scale Empty Chromatography Column

Chrom-LinX® Lab-scale Empty Chromatography Column are made of biocompatible materials with good chemical tolerance. The columns can be used in aqueous solutions and almost all the organic solvents commonly used in liquid chromatography of macromolecules. The columns intolerant of chlorinated hydrocarbons, acetone and other ketones, aliphatic esters, and phenol. The columns are not allowed to use the solution containing more than 2 M NaOH, 1 M HCl, other strong mineral acids, or 75% acetic acid.

No.

Name

1

Adjustable capital

2

Column tube

3

Fixed capital

4

O-ring

5

Support screen

6

Net ring

7

Tubing

Large Glass Chromatography Columns

Fig 3. Details of the Chrom-LinX® Lab-scale Empty Chromatography Column

Instructions of Chrom-LinX® Lab-scale Empty Chromatography Column

Chrom-LinX® Lab-scale Empty Chromatography Column may be used at temperatures from 4° C to 40° C and pressures up to 20 bar (2 MPa, 290 psi) with inner diameters of 10 mm, 16 mm and 26 mm, and 7 bar (0.7 MPa, 101.5 psi) with an inner diameter of 50 mm.

Always clean the column and components with purified water before using.

When packing the column, the double top cap can be rotated, and the threaded shaft moves axially. This operation makes the resins easy to compress. If necessary, column packing can be performed using either a packing tube (Fig 4) or an extra column tube attached with a packing connector.


Packed Column Chromatography


Packing tube operations of the Chrom-LinX® Lab-scale Empty Chromatography Column


Specifications of Chrom-LinX® Lab-scale Empty Chromatography Column

Empty column

Table 1. Parameter of the Chrom-LinX® Lab-scale Empty Chromatography Column

Product code* Column** Column height (mm) Bed height (mm) Bed volume (ml)
2110-1111 Chrom-LinX® 10/200 200 0-155 0-12
2110-1112 Chrom-LinX® 10/400 400 225-355 18-28
2110-1122 Chrom-LinX® 10/400P 400 0-355 0-28
2116-1111 Chrom-LinX® 16/200 200 0-155 0-31
2116-1112 Chrom-LinX® 16/400 400 225-355 45-71
2116-1122 Chrom-LinX® 16/400P 400 0-355 0-71
2116-1113 Chrom-LinX® 16/700 700 525-655 105-132
2116-1123 Chrom-LinX® 16/700P 700 355-655 71-132
2116-1114 Chrom-LinX® 16/1000 1000 825-955 166-192
2116-1124 Chrom-LinX® 16/1000P 1000 655-955 132-192
2126-1111 Chrom-LinX® 26/200 200 0-155 0-82
2126-1112 Chrom-LinX® 26/400 400 225-355 119-188
2126-1122 Chrom-LinX® 26/400P 400 0-355 0-188
2126-1113 Chrom-LinX® 26/700 700 525-655 278-347
2126-1123 Chrom-LinX® 26/700P 700 355-655 188-347
2126-1114 Chrom-LinX® 26/1000 1000 825-955 438-507
2126-1124 Chrom-LinX® 26/1000P 1000 655-955 347-507
2150-1111 Chrom-LinX® 50/200 200 0-155 0-304
2150-1112 Chrom-LinX® 50/400 400 225-355 441-697
2150-1122 Chrom-LinX® 50/400P 400 0-355 0-697
2150-1113 Chrom-LinX® 50/700 700 525-655 1030-1285
2150-1123 Chrom-LinX® 50/700P 700 355-655 697-1285
2150-1114 Chrom-LinX® 50/1000 1000 825-955 1619-1874
2150-1124 Chrom-LinX® 50/1000P 1000 655-955 1285-1874

* The specifications of the following item numbers are 1 per package

** The ''P'' after the column stands for equipped with two adjustable capitals


Packing tube

Product code Product name No. per pack
2720-1001 10 packing tube 1
2720-1601 16 packing tube 1
2720-2601 26 packing tube 1
2720-5001 50 packing tube 1

Spare and accessory parts

Product code * 10mm 16mm 26mm 50mm No. per pack
O-ring 2719-1003 2719-1603 2719-2603 2719-5003 5
Support screen 2721-1001 2721-1601 2721-2601 2721-5001 5
Net ring, 10 μm 2724-1011 2724-1611 2724-2611 2724-5011 5
Net ring, 5 μm 2724-1052 2724-1652 2724-2652 2724-5052 5
Adjustable capital 2730-1001 2730-1601 2730-2601 2730-5001 1
Column tube 200mm 2731-1001 2731-1601 2731-2601 2731-5001 1
Column tube 400mm 2731-1002 2731-1602 2731-2602 2731-5002 1
Column tube 400mm, P 2731-1012 2731-1612 2731-2612 2731-5012 1
Column tube 700mm - 2731-1603 2731-2603 2731-5003 1
Column tube 700mm, P - 2731-1613 2731-2613 2731-5013 1
Column tube 1000mm - 2731-1604 2731-2604 2731-5004 1
Column tube 1000mm, P - 2731-1614 2731-2614 2731-5014 1
Fixed capital 2732-1001 2732-1601 2732-2601 2732-5001 1
Union, 10-32 2726-1001 2726-1001 2726-1001 - 10
Union, 10-32 to 5-16 - - - 2726-1002 10
Union, 10-32 to M6 - - - 2726-1003 10
Union, 10-32 to luer taper 2726-1004 2726-1004 2726-1004 - 10
Union, 3-16 - - - 2726-3101 10
Union, 1-8 - - - 2726-1801 10
Stop plug, male, 10-32 2727-1001 2727-1001 2727-1001 - 10
Stop plug, female, 10-32 2727-1002 2727-1002 2727-1002 - 10
Bi-pass, 10-32 2728-1001 2728-1001 2728-1001 - 10
Bi-pass, M6 - - - 2728-0601 10
Ferrules for 1/16" 2725-1601 2725-1601 2725-1601 - 5
Ferrules for 1/8" - - - 2725-1801 5
PEEK tubing, 0.75 mm i.d. 2729-1601 2729-1601 2729-1601 - 2 m
PEEK tubing, 2 mm i.d. - - - 2729-1801 2 m
Capillary tubing, 0.75 mm i.d. 2733-1601 2733-1601 2733-1601 - 2 m
Capillary tubing, 1.6 mm i.d. - - - 2733-1801 2 m
Accessory kit** 2723-1001 2723-1601 2723-2601 2723-5001 1

* The "P" after the column stands for equipped with two adjustable capitals.

** The accessory kit includes 2 stop plugs (female), 2 union, 2 O-ring and 2 support screen (10 μm).

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