Product Name:

Rhinogen ^® AP3, Ansamitocin P-3, Ansamitocin P-3 from Actinosynnema pretiosum

Chemical Information:

Molecular formula : C ₃₂ H ₄₃ ClN ₂ O ₉

Molecular weight : 635.14

CAS No.: No. 66584-72-3

background:

Ansamitocin P-3 is a macrolide antibiotic with multiple pharmacological activities such as anti-tumor, anti-tuberculosis, and anti-bacterial. Ansamitocin is synthesized by the fermentation method of Actinomycetes. Its components include P-0, P-1, P-2, P-3, P-3', P-4 and P-4', and Ansamitocin P-3 is the main product. Ansamitocin P-3 is chemically converted into maytansine . Because maytansine has strong cytotoxicity, it can be used as a "warhead" to synthesize antibody-drug conjugates (ADCs) with monoclonal antibodies.
Rhinogen ^® Ansamitocin P-3 is a white powder that is easily soluble in solvents such as methanol, acetone, chloroform, and acetonitrile. The purity of Rhinogen ^{® Ansamitocin P-} 3 monomers can reach more than 93%, and the purity of homologues can reach more than 98%. The recommended storage temperature is 2~8℃.
Rhinozyme has developed a production process with independent intellectual property rights based on its fermentation technology platform, with fermentation production scale ranging from 200L to 6000L. Rhinogen ® Ansamitocin P-3 has a variety of purity and packaging specifications (customized packaging can also be requested by customers) to meet the production needs of different scientific research customers and industrial customers.

Rhinogen ^® Ansamitocin P-3 Advantages:

1. High product purity;
2. Large-scale production, single batch large packaging supply, to meet the industrial customers' requirements for product quality.