background:

A crystallizable fragment consisting of the carboxyl-terminal halves of two immunoglobulin heavy chains linked to each other by disulfide bonds. The Fc fragment contains the carboxyl-terminal portions of the heavy chain constant regions that are responsible for the effector functions of immunoglobulins (complement fixation, binding to cell membranes via the Fc receptor, and placental transport). IgG1 Fc has been reported to have a novel role as a potential anti-inflammatory agent for the treatment of human autoimmune diseases.

Overview:

Antigen name: Human IgG1 Fc Protein, Flag Tag;

Other names: IgG1 type;

Sequence source: Human IgG1 Fc (C103S), Flag Tag (IG1-H52C9) expressed by human 293 cells (HEK293), with Flag tag;

Molecular Weight: The calculated molecular weight of this protein is 27.1 kDa . Due to glycosylation, the protein migrates at 28-33 kDa under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen ^® recombinant human IgG1 Fc protein (Flag tag) packaging specifications are as follows:

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.