background:

A crystallizable fragment consisting of the carboxyl-terminal halves of two immunoglobulin heavy chains linked to each other by disulfide bonds. The Fc fragment contains the carboxyl-terminal portions of the heavy chain constant regions that are responsible for the effector functions of immunoglobulins (complement fixation, binding to cell membranes via the Fc receptor, and placental transport). IgG1 Fc has been reported to have a novel role as a potential anti-inflammatory agent for the treatment of human autoimmune diseases.

Overview:

Antigen name: Human IgG1 Fc Protein, His Tag;

Other names: IgG1 type;

Sequence source: human IgG Fc, His tag (IG1-H5225) expressed by human 293 cells (HEK293) with His tag;

Molecular Weight: The calculated molecular weight of this protein is 26.9 kDa . Due to glycosylation, the protein migrates at 30-33 kDa under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen ^® recombinant human IgG1 Fc protein (His tag) packaging specifications are as follows:

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.