background:

Human CD30, also known as TNFRSF8, is a cell membrane protein and tumor marker of the tumor necrosis factor receptor family. TNFRSF-8 is expressed by activated T cells and B cells, but not by resting T cells. In addition, CD30 is expressed on classical Hodgkin lymphoma cells together with CD15. CD30 is a receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5 and mediate signal transduction leading to NF-κ-B activation. TNFRSF8 may play a role in regulating cell growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis and has also been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body from autoimmunity.

Overview:

Antigen name: Human CD30 / TNFRSF8 Protein, His Tag;

Other names: TNFRSF8, CD30, D1S166E, Ki-1;

Sequence source: human CD30, His tag (CD0-H52H5) expressed by human 293 cells (HEK293) with His tag;

Molecular Weight: The calculated molecular weight of this protein is 40.4 kDa . Due to glycosylation, the protein migrates between 53-80 kDa when calibrated against the Star Ribbon prestained protein marker under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen ^® recombinant human CD30 / TNFRSF8 protein (His tag) packaging specifications are as follows:

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.