background:

Hepatitis A virus cellular receptor 1, also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed in the kidney and testes, with the highest levels. The protein encoded by the HAVCR1 gene is a membrane receptor for human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the regulation of asthma and allergic diseases. The reference genome represents an allele that retains the MTTVP amino acid fragment that protects HHAV seropositive individuals from atopy. Three transcript variants of this gene encoding the same protein have been found. HAVCR1 may play a role in T helper cell development, regulation of asthma and allergic diseases, and renal injury and repair. In the context of human hepatitis A virus (HHAV) infection, functions as a cell surface receptor for the virus.

Overview:

Antigen name : Human TIM-1 / HAVCR1 Protein, His Tag;

Other names : Hafke 1, Jin 1, Tim 1, Timde 1;

Sequence source : Human TIM-1 / HAVCR1, His tag (KI1-H52H3) expressed by human 293 cells (HEK293), with His tag;

Molecular Weight : The calculated molecular weight of this protein is 31.5 kDa . Due to glycosylation, the protein migrates at 60-100 kDa under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen ^® recombinant human TIM-1 / HAVCR1 protein (His tag) packaging specifications are as follows:

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 90%.

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.