background:

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta, and melanocytes. Weakly expressed in thyroid, ovary, brain, heart, and skeletal muscle. Also expressed in erythroleukemic cells. Inactive tyrosine kinase involved in the Wnt signaling pathway. Component of both the non-canonical (also known as Wnt /planar cell polarity signaling) and canonical Wnt signaling pathways. Plays a role in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. Plays a role in embryogenesis, epithelial tissue organization, and angiogenesis.

Overview:

Antigen name : Human PTK7 / CCK4 Protein, Fc Tag;

Other names : PTK7, CCK4, CCK-4, tyrosine protein kinase-like 7, protein tyrosine kinase 7, protein tyrosine kinase 7;

Sequence source : Human PTK7, Fc tag (PT7-H5253) expressed in human 293 cells (HEK293) with Fc tag;

Molecular Weight : The calculated molecular weight of this protein is 101.1 kDa . Due to glycosylation, the protein migrates at 125-140 kDa under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen® recombinant human PTK7/CCK4 protein (Fc tag) packaging specifications are as follows ^:

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.