background:

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (cluster of differentiation 123), is a 70 kD glycoprotein member of the hematopoietic receptor superfamily. The protein binds to the β subunit shared by the IL-5 receptor and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor alpha chain (CD123) has been identified as a potential immunotherapy target because it is overexpressed in AML compared to normal hematopoietic stem cells.

Overview:

Antigen name : Human IL-3 R alpha / CD123 Protein, Fc Tag;

Other names : IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha;

Sequence source : Human IL-3 R alpha protein Fc tag (ILA-H5252) expressed by Human 293 cells (HEK293) with Fc tag;

Molecular Weight : The calculated molecular weight of this protein is 59.5 kDa . Due to glycosylation, the protein migrates at 70-90 kDa under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen® recombinant human IL ^- 3 R alpha / CD123 protein (Fc tag) packaging specifications are as follows:

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.