background:

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2), also known as butyricin B7-DC, CD antigen CD273, belongs to the immunoglobulin superfamily or BTN/MOG family. PD-L2 expression is upregulated in monocytes by IFNG/IFN-γ stimulation and induced on dendritic cells grown from peripheral blood monocytes with CSF2 and IL-4. PD-L2 participates in co-stimulatory signals and is essential for T cell proliferation and IFNG production, independent of PDCD1. The interaction of PD-L2 with PDCD1 inhibits T cell proliferation by blocking cell cycle progression and cytokine production.

Overview:

Antigen name : Human PD-L2 / B7-DC Protein, His Tag;

Other names : PDL2, PD-L2, troponin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2;

Sequence source : Human PD-L2 protein Fc tag (PD2-H5251) is expressed by human 293 cells (HEK293) with Fc tag;

Molecular Weight : The calculated molecular weight of this protein is 49.2 kDa . Due to glycosylation, the protein migrates at 60-70 kDa when calibrated against the Star Ribbon prestained protein marker under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen® recombinant human PD-L2/B7-DC protein (His tag) packaging specifications are as follows ^:

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.