background:

TROP-2 is a single-copy gene in human cells that encodes a type 1 transmembrane glycoprotein that is overexpressed in various malignancies and is also known as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1, or M1S1. TROP-2 is associated with epithelial cell adhesion molecule ( EpCAM ), also known as TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II binding protein and appear as signal transducers. Therefore, they may represent new cell surface receptors and may play a role in regulating the growth of cancer cells.

Overview:

Antigen name: Human TROP-2 / TACSTD2 Protein, Fc Tag;

Other names: TACSTD2, GA733-1, M1S1, TROP2;

Sequence source: Human TROP-2, Fc tag (TR2-H5253) expressed by human 293 cells (HEK293) with Fc tag;

Molecular Weight: The calculated molecular weight of this protein is 54.3 kDa . Due to glycosylation, the protein migrates at 60-70 kDa under reducing conditions (SDS-PAGE) .

Packing Specifications:

Rhinogen ^® recombinant human TROP-2 / TACSTD2 protein (Fc tag) packaging specifications are as follows:

characteristic:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.

Storage temperature:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.