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Detailed Introduction
background :
Mesothelin
(MSLN) is also known as CAK1 antigen, pro-megakaryocytic enhancer factor, and
belongs to the mesothelin family. Mesothelin/MSLN can be proteolytically
cleaved by furin -like convertase into two chains: megakaryocytic enhancer
factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form
of mesothelin are N-glycosylated. Mesothelin/MSLN can interact with MUC16. The
membrane-anchored form of MSLN may play a role in cell adhesion. MPF enhances
megakaryocyte colony formation in vitro.
Overview :
Antigen name: Human Mesothelin / MSLN (296-580) Protein, Fc Tag; Other names:
MSLN, Mesothelin, MPF; Sequence source: Human Mesothelin (296-580), Fc tag
(MSN-H526x) expressed by human 293 cells (HEK293) with Fc tag;
Molecular weight: The calculated molecular weight of the protein is 59.1 kDa .
Due to glycosylation, the protein migrates at 60-68 kDa under reducing (R)
conditions (SDS-PAGE) .
Packaging specifications :
Rhinogen ® recombinant human Mesothelin / MSLN (296-580) protein (Fc
tag) packaging specifications are as follows
|
Part Number |
Packing volume |
|
QRE-214-A |
100 μg |
Characteristics :
Purity: Purity in SDS-PAGE reduction electrophoresis>95%.
Storage temperature :
This product can be stored for 12 months in a freeze-dried state at -20°C to -70°C; after reconstitution, it can be stored for 3 months at -70°C under sterile conditions. Please avoid repeated freezing and
thawing.




