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T cell surface glycoprotein CD4 is also called T cell surface antigen T4/Leu-3. CD4 contains 3 Ig -like C2-type (immunoglobulin-like) domains and 1 Ig -like V-type (immunoglobulin-like) domain. CD4 is an accessory protein for MHC class II antigen/T cell receptor interactions. CD4 induces lipid raft aggregation . CD4 is the primary receptor used by HIV-1 to enter host T cells. HIV infection causes a gradual decrease in the number of T cells with CD4 receptors. Therefore, healthcare professionals refer to the CD4 count to decide when to start treatment for HIV-infected patients.

Overview:

Antigen name : Human CD4 Protein, Fc Tag;

Other names : CD4, CD4mut, LEU3;

Sequence source : Human CD4 protein Fc Tag (CD4-H5259) expressed by Human 293 cells (HEK293) with Fc tag;

Molecular Weight : The calculated molecular weight of this protein is 67.5 kDa . Due to glycosylation, the protein migrates at 70-80 kDa under reducing (R) conditions (SDS-PAGE) .

Reagent packaging:

Rhinogen ^® Human CD4 Protein, Fc Tag packaging specifications are as follows:

Product Features:

Purity: Purity in SDS-PAGE reduction electrophoresis> 95%.

Storage conditions:

This product can be stored in a freeze-dried state at -20°C to -70°C for 12 months; after reconstitution, it can be stored at -70°C under sterile conditions for 3 months. Please avoid repeated freezing and thawing.