Antigen Name:

Recombinant human LIGHT/TNFSF14 protein (His Tag)/Human LIGHT/TNFSF14Protein, His Tag;

Other Names:

CD258 antigen, CD258, HVEM-L, LIGHT, LTg , TNFSF14, TR2, HVEML;

background:

Tumor necrosis factor ligand superfamily member 14 (LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that modulates T cell immune responses by signaling through herpes virus entry mediator (HVEM) and lymphotoxin beta receptor ( LTbetaR ). LIGHT has emerged as a potent initiator of T cell co-stimulatory signals that influence CTL -mediated tumor rejection, allograft rejection, and graft-versus-host disease. Continuous expression of LIGHT can lead to tissue destruction and autoimmune disease syndromes.

Sequence source:

Human LIGHT / TNFSF14 Protein, His Tag is expressed by Chinese hamster ovary (CHO) cells; protein number is O43557-1 (Asp74 - Val240), with His tag;

Molecular Weight:

The theoretical molecular weight is 20.1 kDa. Due to glycosylation, the molecular weight of SDS-PAGE reduction electrophoresis is 116 kDa.

Specifications:

purity:

SDS-PAGE electrophoresis purity> 80%;

application:

Monoclonal antibody for quantitative detection of HumanLIGHT / TNFSF14 Protein in cell culture medium, serum and milk .

Buffer:

50mM Tris-HCl, 150mM NaCl, pH8.0;

Storage conditions:

This product can be stored at -20℃~-70℃ for 12 months; after reconstitution, it can be stored at -70℃ under sterile conditions for 3 months. Please avoid repeated freezing and thawing.