Antigen Name:

Recombinant human PLAU / uPA protein (His Tag)/Human PLAU / uPA Protein, His Tag;

Other Names:

Urokinase, PLAU, ATF, UPA, URK, u-PA, BDPLT5, QPD;

background:

Urokinase-type plasminogen activator, also known as PLAU and UPA, is a serine protease with extremely limited substrate specificity that cleaves the Cys -Pro-Gly-Arg560-Val561-Val-Gly-Gly- Cys sequence in plasminogen to form plasminogen. uPA and its receptor ( uPAR ) are involved in a variety of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherosclerosis, and plaque destabilization, all of which are involved in the pathogenesis of myocardial infarction (MI).

Sequence source:

Human PLAU / uPA Protein, His Tag, expressed by Chinese hamster ovary (CHO) cells; protein number P00749-1 (Ser21 - Leu431), with His tag;

Molecular Weight:

The theoretical molecular weight is 48.28 kDa. Due to glycosylation, the molecular weights of SDS-PAGE reduction electrophoresis are 17 kDa, 32-35 kDa and 45-50 kDa.

Specifications:

purity:

SDS-PAGE electrophoresis purity> 99%;

application:

Monoclonal antibody for quantitative detection of HumanPLAU / uPA Protein in cell culture medium, serum and milk .

Buffer:

20mM PB, 150mM NaCl, pH7.4;

Storage conditions:

This product can be stored at -20℃~-70℃ for 12 months; after reconstitution, it can be stored at -70℃ under sterile conditions for 3 months. Please avoid repeated freezing and thawing.