Antigen Name:

Human CD38, hFc Tag;

Other Names:

CD38, T10, cADPr hydrolase 1;

background:

CD antigen CD38 is also known as ADP-nucleotide cyclase 1 and belongs to the ADP-ribose cyclase family. CD38 is expressed at high levels in the pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional extracellular enzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (CADPR) from NAD+ to ADP-ribose. These reaction products are essential for regulating intracellular Ca2 ⁺ . Loss of CD38 function is associated with impaired immune response, metabolic disorders and behavioral modification. CD38 protein is a marker of cell activation. It is associated with HIV infection, leukemia, multiple myeloma, solid tumors, type II diabetes and bone metabolism . CD38 has been used as a prognostic marker for leukemia.

Sequence source:

Human CD38, Fc Tag is expressed by Chinese hamster ovary (CHO) cells; protein number is P28907-1 (Val43-Ile300), with hFc tag;

Molecular Weight:

The theoretical molecular weight of the monomer is 56 kDa. Due to glycosylation, the molecular weight of SDS-PAGE non-reducing electrophoresis is 66-70 kDa, which is usually a dimer.

Specifications:

If you need large packages, please contact customer service at 0512-87663137, or send an email to sales@rhinobio.com.

purity:

Purity: SDS-PAGE non-reducing electrophoresis purity> 95%;

application:

As an antigen, antibodies are obtained by immunizing animals; monoclonal antibodies used for quantitative detection of CD38 in cell culture fluid, serum, and milk.

Storage conditions:

This product can be stored at -70℃ for 36 months; at -20℃ for 12 months; at 2-8℃ for 1 month. Please avoid repeated freezing and thawing.