Antigen Name:

Recombinant human CD24 ECD protein ( hFc tag).

background:

Recombinant human CD24 ECD protein ( hFc tag) is a fusion protein of recombinant human CD24 ECD (CD24 molecule) and human IgG1 Fc. The cluster of differentiation (CD) system is often used as a cell marker in immunoassays. Different types of cells in the immune system can be identified by surface CD molecules associated with cellular immune functions. More than 32 unique clusters and subclusters of CD have been identified. Some CD molecules act as receptors or ligands important to cells by initiating signaling cascades that change the behavior of cells. Some CD proteins do not participate in cell signaling processes but have other functions, such as cell adhesion. Cluster of differentiation 24, also known as signal transducer CD24 or heat-stable antigen CD24 (HSA), is a mucin-type glycosylphosphatidylinositol-linked glycoprotein expressed on the surface of B cells, differentiated into neuroblasts and many tumors. It is involved in molecular adhesion and metastatic tumor spread and serves as a normal receptor for P-selectin. The CD24/P-selectin pathway may be important in simplifying tumor cells by promoting interactions with platelets and endothelial cells. It is also considered a tumor marker. High levels of CD24 expression have been found in epithelial ovarian cancer, breast cancer, non-small cell lung cancer, prostate cancer, and pancreatic cancer.

Sequence source:

CD24 is NM_013230.2, and hFc is the human IgG1 Fc region.

Specifications:

purity:

The purity in SDS-PAGE reduction electrophoresis was >95%.

concentration:

1mg/ml.

Buffer:

PBS, PH7.0.

Storage conditions:

This product can be stored at -20℃ for 12 months; at -70℃ for 36 months; at 2-8℃ for 1 month. Please avoid repeated freezing and thawing.